Description
1P-LSD 150mcg Pellets – Precision-Dosed Lysergamide Research Chemical
Product Overview
Our 1P-LSD 150mcg Pellets deliver laboratory-grade precision for advanced psychedelic research and neuropharmacological studies. Each pellet contains exactly 150 micrograms of 1-propionyl-lysergic acid diethylamide (1P-LSD), a lysergamide compound structurally related to LSD-25.
Manufactured under strict quality control protocols, these pellets provide consistent, reproducible dosing essential for legitimate scientific inquiry into serotonin receptor pharmacology, psychedelic neuroscience, and consciousness research.
Research Applications
1P-LSD serves as a critical research tool for investigating:
Serotonin Receptor Pharmacology
- 5-HT2A Agonism – Primary mechanism of psychedelic action
- 5-HT2C Interactions – Modulation of dopamine release
- 5-HT1A Binding – Anxiolytic and antidepressant effects research
Neuroscience & Consciousness Studies
- Default Mode Network Research – Understanding ego dissolution mechanisms
- Neuroplasticity – Dendritic spine formation and synaptic remodeling
- Therapeutic Potential – Treatment-resistant depression and PTSD studies
Comparative Pharmacology
- Prodrug Kinetics – Metabolism to LSD via depropionylation
- Structure-Activity Relationships – N1-substituent effects on receptor binding
- Duration Studies – Onset, peak, and offset timing research
Mechanism of Action
1P-LSD functions as a serotonin receptor agonist, primarily acting on:
| Receptor | Affinity | Effect |
|---|---|---|
| 5-HT2A | High Agonist | Primary psychedelic effects |
| 5-HT2C | Moderate Agonist | Modulatory role |
| 5-HT1A | Partial Agonist | Anxiolytic properties |
| Dopamine D2 | Weak Antagonist | Secondary effects |
Research indicates 1P-LSD acts as a prodrug of LSD, undergoing depropionylation in vivo to produce LSD as the primary active metabolite.
Quality Assurance & Testing
Analytical Verification:
- NMR Spectroscopy (¹H and ¹³C) – Structural confirmation
- HPLC-DAD – Purity quantification (≥99%)
- LC-MS/MS – Molecular weight verification
- Chiral HPLC – Stereochemical purity
- Stability Testing – Degradation profile analysis
Documentation Provided:
- Certificate of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Handling and storage protocol
- Batch-specific chromatograms and spectra
Product Specifications
| Attribute | Details |
|---|---|
| Chemical Name | 1-Propionyl-lysergic acid diethylamide |
| Synonyms | 1P-LSD, 1P-LAD, 1P-Lysergic, Acid Prodrug |
| CAS Number | 2349356-95-4 |
| Molecular Formula | C₂₃H₂₉N₃O₂ |
| Molecular Weight | 379.50 g/mol |
| Appearance | Blue/White micro-pellets (2mm diameter) |
| Dosage Per Pellet | 150 micrograms (±5% variance) |
| Purity | ≥99% (HPLC verified) |
| Pellet Count Options | 5ct, 10ct, 25ct, 50ct, 100ct |
| Storage | -20°C to 4°C, light-protected, desiccated |
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